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Update package documentation.
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AnthonyChristidis committed Oct 25, 2024
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Expand Up @@ -582,35 +582,6 @@ plot(distance_data, ref_cell_type = "CD4", cell_names = cd4_top6_anomalies)

![](https://raw.githubusercontent.com/ccb-hms/scDiagnostics/main/inst/extdata/compressed/scDiagnostics/calculateCellDistances.png)

# Conclusion

In this vignette, we have introduced the core functionalities of the
`scDiagnostics` package, providing a detailed guide on its use for
scRNA-seq data analysis. We started by exploring the basic capabilities,
including the visualization of query versus reference datasets through
dimensionality reduction techniques. This approach allows for both the
evaluation of multiple cell types simultaneously and the comparison of
distributions for individual cell types.

We then delved into the visualization of annotation scores, which is
essential for assessing the accuracy of cell type assignments. Following
this, we discussed statistical methods for evaluating annotation
precision. This includes assessing correlation between cell types and
performing statistical tests to compare two datasets, offering a
rigorous approach to validate cell type classifications.

The vignette also covered techniques for detecting annotation anomalies,
crucial for identifying and addressing potential issues that could
impact data validity. Additionally, we explored cell distance
diagnostics, focusing on analyzing distances between specific cells and
various cell populations or distributions to better understand internal
relationships and variations.

Overall, this guide equips you with practical tools and methods to
enhance the reliability and accuracy of your scRNA-seq data analysis
using `scDiagnostics`, paving the way for more informed and meaningful
biological interpretations.

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