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Chronic_implants
Nick Steinmetz edited this page Mar 20, 2019
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Neuropixels probes can be implanted chronically and carried easily by rats or mice.
On a mouse, an entire implant with steel headplate, acrylic, probe, and 3D-printed enclosure weighed less than 3 grams. The probe was implanted without a microdrive according to the method of Okun et al. 2016. The stl file for the 3D-printed enclosure can be found here.
A holder that can be used for inserting the probe can be seen in the image below. The holder is available from Fine Science Tools (1837444 Moria MC44 Bulldog Clamp Curved 35 mm), and a custom blue plastic piece was attached. Photo (rotated by 90deg) and holder design by Armin Lak.
- About Neuropixels and probe types
- Configurations and selecting electrodes
- Equipment List and example setup
- Probe handling/mounting
- Chronic implants
- Probe sharpening
- Probe care
- Planning probe trajectories
- Acquisition software
- Referencing and Grounding
- Gain settings
- Filter settings
- Impedance testing
- Synchronization
- Multiple probes on one computer
- Light artifacts
- Troubleshooting
- Recommended preprocessing
- Spike sorting
- Spike sorting curation
- Other analysis methods, and tutorial for getting started with Neuropixels Phase3 data in matlab
- Identifying tracks in histology