Releases: davidaknowles/leafcutter
Releases · davidaknowles/leafcutter
v0.2.7
prepare_results.R
forleafviz
received a significant re-write including- Removed dependence on
bedtools
- Friendlier CLI arguments
- New documentation on the doc website
- Removed dependence on
- smart initialization got regularization (deals with co-linear covariates) and robustness to a rare divide-by-zero bug.
v0.2.6
v0.2.5
- Important bugfix for smart initialization when there are no technical/confounding covariates.
v0.2.4
- LeafViz PCA now made with ratios rather than counts
- prepare_results now accepts covariates in support file
- Added magrittr and stringr dependencies
- LeafViz now allows colour and shape of points in PCA to be set to group or covariate
v0.2.3
- Better control of Differential splicing initialization: the default "smart" initialization is now a one-shot method of moments estimator for the null model regression coefficients, but random initialization can be optionally specified, along with the seed (see --init and --seed options of leafcutter_ds.R) (issue #33)
- Dalila Pinto contributed a new script 'gtf2leafcutter.pl' for more robustly converting GTF files to the "annotation code" needed for leafviz. Thanks!
v0.2.2
cluster_table
now includesp.adjust
column calculated using BH FDR control.- Improved gene view in LeafViz
check.names = F
when reading counts files to avoid issues with sample file names getting changed by R- Removed
-w
option from shebang in perl scripts since this was causing issues on Linux (fine on Mac)
v0.2
- Merged
covariates
branch, allow for controlling for confounders. - Merged
newstansyntax
branch, reduces warnings fromrstan
. - Added leafvis
shiny
app.