For the first time, we implemented the causal inference theories on the construction of microbial interaction networks with cross-sectional microbiome dataset. Subsequently, the keystone species of NAFLD were identified by dynamic intervention modeling (DIM) with the interaction networks.
How to cite this article: Wu, Dingfeng, Lei Liu, Na Jiao, Yida Zhang, Li Yang, Chuan Tian, Ping Lan, Lixin Zhu, Rohit Loomba, and Ruixin Zhu. 2022. “Targeting Keystone Species Helps Restore the Dysbiosis of Butyrate‐Producing Bacteria in Nonalcoholic Fatty Liver Disease.” iMeta e61. https://doi.org/10.1002/imt2.61