This repository included all the codes, dataset and other materials regarding our publication: Mathematical modeling insights into improving CAR T cell therapy for solid tumors with bystander effects at NPJ System Biology and Its Applications. Here is a brief explanation the material present in the repo:
data: this folder has the data we extracted from Klampatsa et.al.
meta_data: data we generated during our analysis.
virtual_patient_analysis: Matlab codes for generation and analysis of two virtual patient cohorts.
data_analysis.ipynb: Python code to reproduce most of the results in the paper. Detailed explanations are
provided in the corresponding sections of the notebook.Other Matlab codes are self-explanatory with more descriptions within them. Please let us know if you need any question or help. You can send an email to erdikara@spelman.edu. If you find this repo useful please cite as
@article{kara2024mathematical,
title={Mathematical modeling insights into improving CAR T cell therapy for solid tumors with bystander effects},
author={Kara, Erdi and Jackson, Trachette L and Jones, Chartese and Sison, Rockford and McGee II, Reginald L},
journal={npj Systems Biology and Applications},
volume={10},
number={1},
pages={105},
year={2024},
publisher={Nature Publishing Group UK London}
}