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Irina edited this page Jan 14, 2016
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The goals of this project were:
- to explore a number of cell types potentially valuable for a better understanding of ankylosing spondylitis (one of which, GMCSF+IL17A+IFN-, was described for the first time);
- to suggest a list of differentially expressed genes in healthy controls vs AS patients;
- to suggest a list of affected pathways in healthy controls vs AS patients.
| Project ID | mRNA in AS |
|---|---|
| Status | Ongoing |
| Dates | 2015-2016 |
| Publication | Unplished |
| Ethics | ??? |
| Sample information | |
|---|---|
| Organism | Human |
| Organism part | Blood |
| Cell type | CSF+, IL17A+, IFN+, IL17A+GMCSF+IFN-, CD45RA+Cyt |
| Experimental conditions | healthy volunteers and patients with AS |
| Phenotype | Healthy and Ankylosing spondylitis |
| Sample source | ??? |
| Sequencing project ID | Data type | Platform | Repository name *1 | Repository ID *2 | Data release status | Analysis *3 | Script Repository |
|---|---|---|---|---|---|---|---|
| P150188 | mRNA sequencing | Illumina Hiseq4000 | on rescomp1: /well/jknight/Irina/Hussein_mRNA_GMCSF/ | ??? | NA | differential expression of mRNA; pathway analysis | https://github.com/jknightlab/hussein_rnaseq/blob/master/Workflow_simplified.md |
- *1 - Name of public data repository to which data has been submitted
- *2 - ID assigned by repository
- *3 - Brief description of analysis. Include links to scripts in Git repository and pages describing results where possible.
| Contact information | |
|---|---|
| Contact1, name and email | Irina Pulyakhina, irina@well.ox.ac.uk |