Skip to content

Optimal AlphaMissense threshold based on VKGL variant classifications

Notifications You must be signed in to change notification settings

joerivandervelde/alphamissense-vkgl-threshold

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 

History

2 Commits
 
 
 
 
 
 

Repository files navigation

The optimal AlphaMissense threshold based on 52799 VKGL variant classifications is 0.2977 with PPV 61%, NPV 96%, sensitivity 87% and specificity 86%.

AM-VKGL-thr-dens

Sanity check (i.e. verification): re-determining AlphaMissense's own threshold using AlphaMissense classifications resulting from applying that same threshold. The optimal AlphaMissense threshold based on AlphaMissense's own classifications is 0.5641 with PPV 100%, NPV 100%, sensitivity 100% and specificity 100%.

AM-AM-thr-dens

About

Optimal AlphaMissense threshold based on VKGL variant classifications

Topics

Resources

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published

Languages