Use non-model library for testing cases

nlmixr2 · May 16, 2024 · 053b10e · 053b10e
1 parent a14325e
commit 053b10e
Show file tree

Hide file tree

Showing 6 changed files with 32 additions and 4 deletions.
diff --git a/inst/cov/bolus_1cpt_Vk.txt b/inst/cov/bolus_1cpt_Vk.txt
@@ -0,0 +1,14 @@
+DESCRIPTION:
+The administration is via a bolus.
+The PK model has one compartment (volume V) and a linear elimination (elimination rate k).
+
+
+[LONGITUDINAL]
+input = {V, k}
+
+PK:
+; PK model definition
+Cc = pkmodel(V, k)
+
+OUTPUT:
+output = Cc
diff --git a/inst/cov/oral1_1cpt_TlagkaVCl.txt b/inst/cov/oral1_1cpt_TlagkaVCl.txt
@@ -0,0 +1,14 @@
+DESCRIPTION:
+The administration is extravascular with a first order absorption (rate constant ka) and a lag time (Tlag).
+The PK model has one compartment (volume V) and a linear elimination (clearance Cl).
+
+
+[LONGITUDINAL]
+input = {Tlag, ka, V, Cl}
+
+PK:
+; PK model definition
+Cc = pkmodel(Tlag, ka, V, Cl)
+
+OUTPUT:
+output = Cc
diff --git a/inst/cov/phenobarbital_project.mlxtran b/inst/cov/phenobarbital_project.mlxtran
@@ -43,7 +43,7 @@ k = {distribution=logNormal, typical=k_pop, sd=omega_k}
 [LONGITUDINAL]
 input = {b}
 
-file = 'lib:bolus_1cpt_Vk.txt'
+file = 'bolus_1cpt_Vk.txt'
 
 DEFINITION:
 CONC = {distribution=normal, prediction=Cc, errorModel=proportional(b)}

diff --git a/inst/cov/warfarin_covariate1_project.mlxtran b/inst/cov/warfarin_covariate1_project.mlxtran
@@ -36,7 +36,7 @@ Cl = {distribution=logNormal, typical=Cl_pop, sd=omega_Cl}
 [LONGITUDINAL]
 input = {a, b}
 
-file = 'lib:oral1_1cpt_TlagkaVCl.txt'
+file = 'oral1_1cpt_TlagkaVCl.txt'
 
 DEFINITION:
 concentration = {distribution=normal, prediction=Cc, errorModel=combined1(a, b)}

diff --git a/inst/cov/warfarin_covariate2_project.mlxtran b/inst/cov/warfarin_covariate2_project.mlxtran
@@ -39,7 +39,7 @@ Cl = {distribution=logNormal, typical=Cl_pop, covariate=lw70, coefficient=beta_C
 [LONGITUDINAL]
 input = {a, b}
 
-file = 'lib:oral1_1cpt_TlagkaVCl.txt'
+file = 'oral1_1cpt_TlagkaVCl.txt'
 
 DEFINITION:
 concentration = {distribution=normal, prediction=Cc, errorModel=combined1(a, b)}

diff --git a/inst/cov/warfarin_covariate3_project.mlxtran b/inst/cov/warfarin_covariate3_project.mlxtran
@@ -51,7 +51,7 @@ Cl = {distribution=logNormal, typical=Cl_pop, covariate=tSex, coefficient={beta_
 [LONGITUDINAL]
 input = {a, b}
 
-file = 'lib:oral1_1cpt_TlagkaVCl.txt'
+file = 'oral1_1cpt_TlagkaVCl.txt'
 
 DEFINITION:
 concentration = {distribution=normal, prediction=Cc, errorModel=combined1(a, b)}