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[NTR-pcl] L4 IT (Mus MOp) #226
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This was referenced Dec 9, 2021
shawntanzk
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Dec 16, 2021
Fixes #226 Note given the rest of IT aren't species restricted, I opted to make this species agnostic too
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Preferred term label:
L4 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus)
Synonyms
L4 IT MOp (Mus)
Definition (free text, please give PubMed ID in format PMID:XXXXXX)
An intratelencephalic-projecting glutamatergic neuron that is located in the boundary between L2/3 and L5 of the primary motor cortex. These cells have diverse morphologies with some pyramidal and some stellate cells.
PMID:33184512
Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols/ontologies/cl):
glutamatergic neuron
What is the anatomical structure that the cell is a part of? Please check Uberon: https://www.ebi.ac.uk/ols/ontologies/uberon
http://purl.obolibrary.org/obo/UBERON_0001384 - Primary Motor Cortex
*has some soma location, can specify layer
Your nano-attribution (ORCID)
Any additional notes or concerns
xref:(ILX:0770172)
Subclass of L2/3-6 IT projecting neuron #878
Not sure if I should include the following information:
Likely corresponded to the quasi-L4 neurons described previously in the motor cortex. PMID:25525751.
The paper quoted also writes: (1) input of primary thalamocortical (TC) axons from VL and PO; (2) output to excitatory neurons in other layers, especially L2/3; (3) largely unidirectional L4→2/3 projections (i.e., little input in return from L2/3), and often, although not as a strict rule, (4) a paucity of long-range corticocortical inputs and outputs.
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