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Text def Purkinje neuron (#2438)
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* Text def Purkinje neuron

Fixes #2176

* Update cl-edit.owl

* Update cl-edit.owl
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@AvolaAmg
AvolaAmg authored Jul 18, 2024
1 parent 5c92a14 commit 1fe8d93
Showing 1 changed file with 6 additions and 5 deletions.
11 changes: 6 additions & 5 deletions src/ontology/cl-edit.owl
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Expand Up @@ -4623,14 +4623,15 @@ SubClassOf(obo:CL_0000120 obo:CL_0000117)

# Class: obo:CL_0000121 (Purkinje cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D011689") obo:IAO_0000115 obo:CL_0000121 "The output neuron of the cerebellar cortex.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D011689") Annotation(oboInOwl:hasDbXref "PMID:12907269") Annotation(oboInOwl:hasDbXref "PMID:14568361") Annotation(oboInOwl:hasDbXref "PMID:31424738") Annotation(oboInOwl:hasDbXref "PMID:33288911") Annotation(oboInOwl:hasDbXref "PMID:38168772") obo:IAO_0000115 obo:CL_0000121 "An inhibitory neuron and the sole output neuron of the cerebellar cortex, the Purkinje cell's soma is located between the granular and molecular layers of the cerebellum. It is one of the largest neural cells in the mammalian brain, ranging from 50 to 80 micrometres in diameter. Purkinje cells have planar, fan-shaped dendrites that branch extensively with little overlap. This cell type receives synaptic input from parallel fibres, which modulate high-frequency spike activity known as \"simple spikes,\" and climbing fibres, which modulate infrequent calcium spike activity known as \"complex spikes\". Purkinje cells are involved in motor coordination, particularly in correcting movements in progress.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "BTO:0001011")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "CALOHA:TS-0845")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "FMA:67969")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000121 "Purkinje neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000121 "Purkinje's cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000121 "cerebellar Purkinje cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000121 "cerebellum Purkinje cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28821816") oboInOwl:hasExactSynonym obo:CL_0000121 "Purkinje neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.proghi.2004.07.002") oboInOwl:hasExactSynonym obo:CL_0000121 "cerebellar Purkinje cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38168772") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000121 "PC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28821816") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000121 "PN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17535929") Annotation(oboInOwl:hasDbXref "PMID:27215193") Annotation(oboInOwl:hasDbXref "PMID:37426070") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.stem.2023.11.013") rdfs:comment obo:CL_0000121 "Neurodegenerative disorders affecting Purkinje cells disrupt motor functions. Some of the neurodegenerative disorders that causes loss and degeration of Purkinje cells are Spinocerebellar ataxias (SCAs) (Josef P Kapfhammer and Etsuko Shimobayashi 2023), Friedreich's ataxia (FRDA) (Kevin C Kemp et al., 2016), Fetal alcohol syndrome (Laurent Servais et al., 2016), Dandy-Walker malformation (Alexander Atamian et al., 2024).")
AnnotationAssertion(rdfs:label obo:CL_0000121 "Purkinje cell")
SubClassOf(obo:CL_0000121 obo:CL_0000117)
SubClassOf(obo:CL_0000121 obo:CL_0000527)
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