Tian (2003)

Description

The authors investigated the purified plasma cells from the bone marrow of control patients along with patients with newly diagnosed multiple myeloma. Expression profiles for 12,2625 genes were obtained via Affymetrix U95Av2 microarrays. The plasma cells were subjected to biochemical and immunohistochemical analyses to identify molecular determinants of osteolytic lesions. For 36 multiple-myloma patients, focal bone lesions could not be detected by magnetic resonance imaging (MRI), whereas MRI was used to detect such lesions in 137 patients.

Sample Size	Number of Features	Number of Classes	Disease
173	12,625	2	Myeloma

Reference

Link to Original Paper

BibTeX Record

@article{Tian:2003ht,
author = {Tian, Erming and Zhan, Fenghuang and Walker, Ronald and Rasmussen, Erik and Ma, Yupo and Barlogie, Bart and Shaughnessy, Jr., John D},
title = {{The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma}},
journal = {New England Journal of Medicine},
year = {2003},
volume = {349},
number = {26},
pages = {2483--2494},
month = dec
}