Image-processing software for cryo-electron microscopy

Computational Crystallography Toolbox

Pipeline for particle picking in cryo-electron microscopy images using convolutional neural networks trained from positive and unlabeled examples. Also featuring micrograph and tomogram denoising with DNNs.

A collaborative list of awesome CryoEM (Cryo Electron Microscopy) resources.

A curated list of awesome computational cryo-EM methods.

Scipion is an image processing framework to obtain 3D models of macromolecular complexes using Electron Microscopy (3DEM)

Self-supervised learning for isotropic cryoET reconstruction

Deep learning for cryo-EM maps post-processing

Leveraging Structural Priors and Constraints for Cryo-EM Heterogeneous Reconstruction

pytorch implementation of noise2noise for Cryo-EM image denoising

register 3D point clouds using rotation, translation, and scale transformations.

DiffModeler: a diffusion model based protein complex structure modeling tool.

Xmipp is a suite of image processing programs, primarily aimed at single-particle 3D electron microscopy.

High Throughput Electron Microscopy Image Processing Software

deep structural disentanglement

ArtiaX is an open-source extension of the molecular visualisation program ChimeraX.

cryo-ET particle picking by representation and metric learning

Python library that enables scripting access to CryoSPARC, a cryo-EM software package.

CryoREAD: a computational tool using deep learning to automatically build full DNA/RNA atomic structure from cryo-EM map.

TomoBEAR is a configurable and customizable modular pipeline for streamlined processing of cryo-electron tomographic data for subtomogram averaging.