LOBSTAHS 1.19.1

Includes:

• Updated copyright dates
• Updated list of authors to account for personnel changes
• Bug fix for handling new compounds that are not acyl iteration species
• Synchronizes Van Mooy Lab GitHub repository with current version of Bioconductor

LOBSTAHS 1.5.0

This release includes an updated default database with two new lipid classes, PA and LPA.

LOBSTAHS 1.3.6

This release includes an updated default database with several new lipids and lipid classes.

LOBSTAHS 1.3.3

New arguments to the doLOBscreen and getLOBpeaklist functions now allow the user to retain data for all features in the original xsAnnotate object — those that were not identified or were discarded during the screening process, in addition to data for those features to which a compound assignment was applied from the database. This is useful when untargeted follow-on data analysis is anticipated, or the user simply wants to export data for all features present in the original dataset, not just those for which a LOBSTAHS identity was found.

LOBSTAHS 1.3.1

Release 1.3.1 contains vignette updates and adds several new compounds to the default databases.

LOBSTAHS 1.1.4

Release 1.1.4 contains significant updates to the primary package vignette. The vignette now contains straightforward instructions for database customization and clarifies the process for adding new lipids/lipid classes to the default databases. The release also updates the vignette to include a flow chart, which illustrates the database customization process in visual form.

LOBSTAHS 1.1.3

Release of 1.1.2 contained a few errors in the masses of new lipid classes BLL, PDPT, and S_DGCC. These have been fixed.

LOBSTAHS 1.1.2

Bioconductor devel release v1.1.2.

More straightforward custom database generation: The database generation function generateLOBdbase has been altered to allow users to add their own new lipid classes and compounds with much less hassle. Addition of most new lipid classes and individual compounds will now require no editing of source code. Instead, users seeking to add their own new compounds and lipid classes to a custom database need only specify values for two additional elements in the basic component matrix (https://github.com/vanmooylipidomics/LOBSTAHS/blob/master/inst/doc/csv/LOBSTAHS_basic_component_matrix.csv) prior to calling generateLOBdbase. Instructions and an explanation are now presented in a revised vignette: https://github.com/vanmooylipidomics/LOBSTAHS/blob/master/vignettes/LOBSTAHS.Rmd

New lipid classes: Release 1.1.2 also includes support for several additional lipid classes, including glycosphingolipids and betaine-like lipids. Data for several of these classes was incorporated from results published in Hunter, J. E., Frada, M. J., Fredricks, H. F., Vardi, A., and Van Mooy, B.A.S. 2015. Targeted and untargeted lipidomics of Emiliania huxleyi viral infection and life cycle phases highlights molecular biomarkers of infection, susceptibility, and ploidy. Front. Mar. Sci. 2: 81; doi:10.3389/fmars.2015.00081

LOBSTAHS 1.1.1

Bioconductor devel release v1.1.1. Includes support for some additional lipid classes. Best way to download is directly from Bioconductor: http://bioconductor.org/packages/devel/bioc/html/LOBSTAHS.html

LOBSTAHS 0.99.8

Downgrade of version number reflects a review of the package currently underway at Bioconductor. Version 0.99.8 is the latest and greatest.